I am an Assistant Professor at Baylor College of Medicine, specializing in computational biology with a focus on integrating spatial transcriptomics and morphological analysis to better understand the tumor microenvironment.
My academic journey began at the University of Ottawa, followed by a Ph.D. from Princeton University, where I developed a strong foundation in computational techniques. My postdoctoral work at Dana-Farber Cancer Institute and Harvard Medical School further refined my expertise, enabling me to contribute significantly to our understanding of complex biological data and its implications in cancer research.
Read MoreIntegrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in African American and
European American patients with TNBC
Q. Zhu*, A. Balasubramanian*, J.R. Asirvatham*, ..., S. Wang, ... , Y. Li, E. Chang, X. Li, R. Aneja, X. H.-F. Zhang, A. Sreekumar
BioRxiv (2024) https://doi.org/10.1101/2024.03.17.585428 * - co-first authors
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Xenomake: a pipeline for processing and sorting xenograft reads from spatial transcriptomic experiments
B.S. Strope, K.E. Pendleton, W.Z. Bowie, G.V. Echeverria, Q. Zhu
Bioinformatics (2024) Accepted
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Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions
T. Liu*, Q. Zhu*, Y. Kai, T. Bingham, S. Wang, H.J. Cha, S. Mehta, T.M. Schlaeger, G. Yuan & S.H. Orkin
Nature Communications (2024) https://doi.org/10.1038/s41467-024-45386-w * - co-first authors
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Giotto, a toolbox for integrative analysis and visualization of spatial expression data
R. Dries*, Q. Zhu*, R. Dong, CH.L. Eng, H. Li, K. Liu, Y. Fu, T. Zhao, A. Sarkar, F. Bao, R.E. George, N. Pierson, L. Cai & G. Yuan
Genome Biology (2021) https://doi.org/10.1101/701680v2. * - co-first authors
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CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
Q. Zhu, N. Liu, S.H. Orkin & G. Yuan
Genome Biology (2019) https://doi.org/10.1186/s13059-019-1802-4
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Direct Promoter Repression by BCL11A Controls the
Fetal to Adult Hemoglobin Switch
N. Liu*, V.V. Hargreaves*, Q. Zhu*, J.V. Kurland, J. Hong, W. Kim, F. Sher, C. Macias-Trevino, ... , G. Yuan, D.E. Bauer, J. Xu, M.L. Bulyk, S.H. Orkin
Cell (2018) https://doi.org/10.1016/j.cell.2018.03.016 * - co-first authors
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Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data
Q. Zhu, S. Shah, R. Dries, L. Cai & G. Yuan
Nature Biotechnology (2018) https://doi.org/10.1038/nbt.4260
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Targeted exploration and analysis of large cross-platform human transcriptomic compendia
Q. Zhu, A.K. Wong, A. Krishnan, M.R. Aure, A. Tadych, R. Zhang, D.C. Corney, C.S. Greene, L.A. Bongo, V.N. Kristensen, M. Charikar, K. Li & O.G. Troyanskaya
Nature Methods (2015) https://doi.org/10.1038/nmeth.3249
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If you have a PhD or MD degree in related area and have interest in our research, welcome join us. See more details, click here
Undergraduate students who have interest in our research, welcome join us. See more details, click here
If you are a graduate student from Quantitative and Computational Bioscience Graduate Program or/and Genetics and Genomics Graduate Program and interested in our research, welcome join us. See more details, click here
Qian Zhu lab
Baylor College of Medicine
One Baylor Plaza
BCM Jewish Building Room 644D
Houston, TX 77030, USA
Qian.Zhu@bcm.edu
